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Journal of Nanobiotechnology

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Journal of Nanobiotechnology is an open access, peer-reviewed, online journal communicating scientific and technological advances in the fields of medicine and biology, with an emphasis in their interface with nanoscale sciences. The journal provides biomedical scientists and the international biotechnology business community with the latest developments in the growing field of Nanobiotechnology.

Biomimetic nanocarriers in cancer therapy: based on intercellular and cell-tumor microenvironment communication

Journal of Nanobiotechnology

by He Mengyuan, Li Aixue, Gu Yongwei, Chai Qingqing, Cai Huanhuan, Liu Xiaoyan and Liu Jiyong

2d ago

Inspired by the concept of “natural camouflage,” biomimetic drug delivery systems have emerged to address the limitations of traditional synthetic nanocarriers, such as poor targeting, susceptibility to identi ..read more

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Co-freezing localized CRISPR-Cas12a system enables rapid and sensitive nucleic acid analysis

Journal of Nanobiotechnology

by Lifeng Zhang, Shihua Luo, Wenbin Li, Wanting Su, Siting Chen, Chunchen Liu, Weilun Pan, Bo Situ, Lei Zheng, Ling Li, Xiaohui Yan and Ye Zhang

3d ago

Rapid and sensitive nucleic acid detection is vital in disease diagnosis and therapeutic assessment. Herein, we propose a co-freezing localized CRISPR-Cas12a (CL-Cas12a) strategy for sensitive nucleic acid det ..read more

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Targeted blood-brain barrier penetration and precise imaging of infiltrative glioblastoma margins using hybrid cell membrane-coated ICG liposomes

Journal of Nanobiotechnology

by Ping Liu, Siyi Lan, Duyang Gao, Dehong Hu, Zhen Chen, Ziyue Li, Guihua Jiang and Zonghai Sheng

3d ago

Surgical resection remains the primary treatment modality for glioblastoma (GBM); however, the infiltrative nature of GBM margins complicates achieving complete tumor removal. Additionally, the blood-brain bar ..read more

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3D-printing hydrogel programmed released exosomes to restore aortic medial degeneration through inhibiting VSMC ferroptosis in aortic dissection

Journal of Nanobiotechnology

by Weitie Wang, Qing Liu, Qiwei Yang, Songning Fu, Dongdong Zheng, Yale Su, Jinyu Xu, Yong Wang, Hulin Piao and Kexiang Liu

3d ago

Aortic dissection (AD) is a devastating disease with a high mortality rate. Exosomes derived from mesenchymal stem cells (exo-MSCs) offer a promising strategy to restore aortic medial degeneration and combat f ..read more

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Personalized mRNA vaccines in glioblastoma therapy: from rational design to clinical trials

Journal of Nanobiotechnology

by Iman Karimi-Sani, Zahra Molavi, Samaneh Naderi, Seyedeh-Habibeh Mirmajidi, Iman Zare, Yasaman Naeimzadeh, Atena Mansouri, Amir Tajbakhsh, Amir Savardashtaki and Amirhossein Sahebkar

3d ago

Glioblastomas (GBMs) are the most common and aggressive malignant brain tumors, presenting significant challenges for treatment due to their invasive nature and localization in critical brain regions. Standard ..read more

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Truncated M13 phage for smart detection of E. coli under dark field

Journal of Nanobiotechnology

by Jiasheng Yuan, Huquan Zhu, Shixinyi Li, Benjamin Thierry, Chih-Tsung Yang, Chen Zhang and Xin Zhou

3d ago

The urgent need for affordable and rapid detection methodologies for foodborne pathogens, particularly Escherichia coli (E. coli), highlights the importance of developing efficient and widely accessible diagnosti ..read more

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Modification of transvaginal polypropylene mesh with co-axis electrospun nanofibrous membrane to alleviate complications following surgical implantation

Journal of Nanobiotechnology

by Tao Guo, Xuechun Hu, Zhe Du, Xiuqi Wang, Jinghe Lang, Jian Liu, Haiyan Xu and Zhijing Sun

5d ago

Surgeries for treating pelvic organ prolapse involving the utilization of synthetic mesh have been associated with complications such as mesh erosion, postoperative pain, and dyspareunia. This work aimed to re ..read more

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NIR-activatable nitric oxide generator based on nanoparticles loaded small-molecule photosensitizers for synergetic photodynamic/gas therapy

Journal of Nanobiotechnology

by Lili Fu, Yan Huang, Xin Shan, Xiao Sun, Xinlei Wang, Xiaoyan Wang, Lingxin Chen and Shui Yu

5d ago

Therapeutic approaches that combine conventional photodynamic therapy (PDT) with gas therapy (GT) to sensitize PDT are an attractive strategy, but the molecular structure design of the complex lacks effective ..read more

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Integrated triple signal amplification strategy for ultrasensitive electrochemical detection of gastric cancer-related microRNA utilizing MoS2-based nanozyme, hybridization chain reaction, and horseradish peroxidase

Journal of Nanobiotechnology

by Jianfeng Ma, Qunyan Yao, Suo Lv, Jiasheng Yi, Dan Zhu, Changfeng Zhu, Lianhui Wang and Shao Su

5d ago

Early diagnosis and treatment of gastric cancer (GC) play a vital role in improving efficacy, reducing mortality and prolonging patients’ lives. Given the importance of early detection of gastric cancer, an el ..read more

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Superior antitumor immune response achieved with proton over photon immunoradiotherapy is amplified by the nanoradioenhancer NBTXR3

Journal of Nanobiotechnology

by Yun Hu, Sébastien Paris, Narayan Sahoo, Qi Wang, Qianxia Wang, Hampartsoum B. Barsoumian, Ailing Huang, Jordan Da Silva, Célia Bienassis, Claudia S. Kettlun Leyton, Tiffany A. Voss, Fatemeh Masrorpour, Thomas Riad, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi…

5d ago

Recent findings suggest that immunoradiotherapy (IRT), combining photon radiotherapy (XRT) or proton radiotherapy (PRT) with immune checkpoint blockade, can enhance systemic tumor control. However, the compara ..read more

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