During replication, expression, and repair of the eukaryotic genome, cellular machinery must access the DNA wrapped around histone proteins forming nucleosomes. These octameric protein·DNA complexes are modular, dynamic, and flexible and unwrap or disassemble either spontaneously or by the action of molecular motors. Thus, the mechanism of formation and regulation of subnucleosomal intermediates has gained ..read more

Physical properties of the polycrystalline materials are mostly determined by their microstructure. As the crystallization process can determine the microstructure, the nucleation, and growth can also control whether the materials will be resulted in single crystalline or polycrystalline. Along with the morphological changes, anisotropic properties of the materials can also be controlled. * As a ..read more

The viscoelastic behavior of soft materials, especially cells and tissues, has been extensively investigated due to its importance in many biological and physiological processes that take place during development and even disease.* Many techniques are used to quantify the mechanical properties of cells, among them micropipette aspiration, optical stretching, deformability cytometry and atomic force microscopy ..read more

Cells communicate with their environments via the plasma membrane and various membrane proteins. Clathrin-mediated endocytosis (CME) plays a central role in such communication and proceeds with a series of multiprotein assembly, deformation of the plasma membrane, and production of a membrane vesicle that delivers extracellular signaling molecules into the cytoplasm.* In the article “Morphological changes ..read more

Flux-closure structures, vortices/antivortices, skyrmions, and merons in oxides, metals and polymers represent non-trivial topologies in which a local polar/magnetic order undergoes quasi-continuous spatial variations in a host crystal lattice. These structures are now extensively studied due to emergent functionalities, but the application of electrical/mechanical fields has so far only served to destroy the polar topologies ..read more

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Collagen is the most abundant structural protein in mammals. * Type I collagen in its fibril form has a characteristic pattern structure that alternates two regions called gap and overlap. The structure and properties of collagens are highly dependent on the water and mineral content of the environment. * In the article “Interfacial water on ..read more

Airflow limitation in obstructive airway disease is characterized by narrowing of the airway lumen from excessive contraction of airway smooth muscle (ASM) and remodeling of the airway wall which includes changes in the extracellular matrix (ECM) of the ASM layer.* Previous studies on human airway smooth muscle cells ( hASMC ) have independently assessed the ..read more

NanoWorld AG CEO Manfred Detterbeck is attending NANOKOREA 2024, the 22nd International #Nanotech Symposium & Exhibition on nanoscale science and technology , which will be held from July 3-5, 2024 at KINTEX (Korea International Exhibition Center), Goyang-si, Gyeonggi-do, South Korea.  http://www.nanokorea-sympo.or.kr/welcome.php This year’s main theme is: Invisible Nano Realizes the Future Will we meet you ..read more

Known as a rising star among carbon nanomaterials, carbon dots (CDs) have attracted considerable interest in various fields in recent years.* In the article “Highly efficient carbon dot-based photoinitiating systems for 3D-VAT printing” Dominika Krok, Wiktoria Tomal, Alexander J. Knight, Alexander I. Tartakovskii, Nicholas T. H. Farr, Wiktor Kasprzyk and Joanna Ortyl describe how they ..read more