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BMC Neuroscience Journal

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BMC Neuroscience is an open access journal publishing original peer-reviewed research articles in all aspects of the nervous system, including molecular, cellular, developmental and animal model studies, as well as cognitive and behavioral research, computational modeling and systems neuroscience.

Brain magnetic resonance imaging in the DE50-MD dog model of Duchenne muscular dystrophy reveals regional reductions in cerebral gray matter

BMC Neuroscience Journal

by Abbe H. Crawford, Natasha L. Hornby, Alerie G. de la Fuente and Richard J. Piercy

22h ago

Duchenne muscular dystrophy is a X-linked disease characterized by severe and progressive muscle weakness, alongside cognitive impairment and a range of neurobehavioral disorders secondary to brain dystrophin ..read more

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Neuroprotective effects of vinpocetine, as a phosphodiesterase 1 inhibitor, on long-term potentiation in a rat model of Alzheimer’s disease

BMC Neuroscience Journal

by Meysam Shekarian, Iraj Salehi, Safoura Raoufi, Masoumeh Asadbegi, Masoumeh Kourosh-Arami and Alireza Komaki

4d ago

Vinpocetine (Vin) is known as a phosphodiesterase 1 inhibitor (PDE1-I) drug with multilateral effects, including antioxidant and anti-inflammatory activity. In this research, we investigated the neuroprotectiv ..read more

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EPO regulates neuronal differentiation of adult human neural-crest derived stem cells in a sex-specific manner

BMC Neuroscience Journal

by Tarek Niemann, Johannes F.W. Greiner, Christian Kaltschmidt and Barbara Kaltschmidt

2w ago

Sexual differences in the biology of human stem cells are increasingly recognized to influence their proliferation, differentiation and maturation. Especially in neurodegenerative diseases such as Alzheimers d ..read more

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KDM4A, involved in the inflammatory and oxidative stress caused by traumatic brain injury-hemorrhagic shock, partly through the regulation of the microglia M1 polarization

BMC Neuroscience Journal

by Jimin Cai, Yang Yang, Jiahui Han, Yu Gao, Xin Li and Xin Ge

2w ago

Microglial polarization and the subsequent neuroinflammatory response and oxidative stress are contributing factors for traumatic brain injury (TBI) plus hemorrhagic shock (HS) induced brain injury. In the pre ..read more

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Pharmacologic antagonism of CB1 receptors improves electrophysiological alterations in Purkinje cells exposed to 3-AP

BMC Neuroscience Journal

by Hoda Ranjbar, Monavareh Soti, Kristi A. Kohlmeier, Mahyar Janahmadi and Mohammad Shabani

2w ago

Although ataxia is associated with cerebellar dysfunction, little is known about the effects of 3-AP exposure on Purkinje cell electrophysiological properties. Here, we evaluated these parameters in cerebellar ..read more

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Retraction Note: Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease

BMC Neuroscience Journal

by Panchanan Maiti, Leela Paladugu and Gary L. Dunbar

3w ago

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BMC Neuroscience Journal

by Emmanuel C. Nwosu, Martha J. Holmes, Mark F. Cotton, Els Dobbels, Francesca Little, Barbara Laughton, Andre van der Kouwe, Frances Robertson and Ernesta M. Meintjes

3w ago

Life-long early ART (started before age 2 years), often with periods of treatment interruption, is now the standard of care in pediatric HIV infection. Although cross-sectional studies have investigated HIV-re ..read more

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Activation of the IL-17/TRAF6/NF-κB pathway is implicated in Aβ-induced neurotoxicity

BMC Neuroscience Journal

by Yulan Liu, Yang Meng, Chenliang Zhou, Juanjuan Yan, Cuiping Guo and Weiguo Dong

3w ago

Neuroinflammation plays a critical role in Amyloid-β (Aβ) pathophysiology. The cytokine, interleukin-17A (IL-17) is involved in the learning and memory process in the central nervous system and its level was r ..read more

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Detection of neuronal OFF periods as low amplitude neural activity segments

BMC Neuroscience Journal

by Christian D. Harding, Mathilde C. C. Guillaumin, Lukas B. Krone, Martin C. Kahn, Cristina Blanco-Duque, Christian Mikutta and Vladyslav V. Vyazovskiy

3w ago

During non-rapid eye movement sleep (NREM), alternating periods of synchronised high (ON period) and low (OFF period) neuronal activity are associated with high amplitude delta band (0.5–4 Hz) oscillations in ..read more

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Non-conscious processing of fear faces: a function of the implicit self-concept of anxiety

BMC Neuroscience Journal

by Vivien Günther, Jonas Pecher, Carolin Webelhorst, Charlott Maria Bodenschatz, Simone Mucha, Anette Kersting, Karl-Titus Hoffmann, Boris Egloff, Donald Lobsien and Thomas Suslow

1M ago

Trait anxiety refers to a stable tendency to experience fears and worries across many situations. High trait anxiety is a vulnerability factor for the development of psychopathologies. Self-reported trait anxi ..read more

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