Vaccines, Vol. 12, Pages 420: Improving Influenza Vaccination Coverage in Patients with Cancer: A Position Paper from a Multidisciplinary Expert Group Vaccines doi: 10.3390/vaccines12040420 Authors: Paolo Bonanni Michele Maio Giordano D. Beretta Giancarlo Icardi Alessandro Rossi Saverio Cinieri Patients with cancer can be immunocompromised because of their disease and/or due to anticancer therapy. In this population, severe influenza virus infections are associated with an elevated risk of morbidity and mortality. Influenza vaccination is therefore highly recommended in cancer patients, includ ..read more

Vaccines, Vol. 12, Pages 415: Sex-Dependent Effects on Influenza-Specific Antibody Quantity and Neutralizing Activity following Vaccination of Newborn Non-Human Primates Is Determined by Adjuvants Vaccines doi: 10.3390/vaccines12040415 Authors: Beth C. Holbrook Elene A. Clemens Martha A. Alexander-Miller A number of studies have demonstrated the role of sex in regulating immune responses to vaccination. However, these findings have been limited to adults for both human and animal models. As a result, our understanding of the impact of sex on vaccine responses in the newborn is highly limited ..read more

Vaccines, Vol. 12, Pages 416: The Effect of an Attenuated Live Vaccine against Salmonid Rickettsial Septicemia in Atlantic Salmon (Salmo salar) Is Highly Dependent on Water Temperature during Immunization Vaccines doi: 10.3390/vaccines12040416 Authors: Rolf Hetlelid Olsen Frode Finne-Fridell Marianne Bordevik Anja Nygaard Binoy Rajan Marius Karlsen Salmonid Rickettsial Septicemia (SRS), caused by the bacterium Piscirickettsia salmonis, is the main reason for antibiotic usage in the Chilean aquaculture industry. In 2016, a live attenuated vaccine (ALPHA JECT LiVac® SRS, PHARMAQ AS ..read more

Vaccines, Vol. 12, Pages 417: Engineered Multivalent Nanobodies Efficiently Neutralize SARS-CoV-2 Omicron Subvariants BA.1, BA.4/5, XBB.1 and BQ.1.1 Vaccines doi: 10.3390/vaccines12040417 Authors: Jiali Wang Bingjie Shi Hanyi Chen Mengyuan Yu Peipei Wang Zhaohui Qian Keping Hu Jianxun Wang Most available neutralizing antibodies are ineffective against highly mutated SARS-CoV-2 Omicron subvariants. Therefore, it is crucial to develop potent and broad-spectrum alternatives to effectively manage Omicron subvariants. Here, we constructed a high-diversity nanobody phage display library and identifi ..read more

Vaccines, Vol. 12, Pages 418: Respiratory Syncytial Vaccination: Parents’ Willingness to Vaccinate Their Children Vaccines doi: 10.3390/vaccines12040418 Authors: Vincenza Sansone Silvia Angelillo Francesca Licata Grazia Miraglia del Giudice Gabriella Di Giuseppe Background: This study was conducted to assess parents’ willingness to vaccinate their children with the RSV vaccine and the key predictors of this intention among parents in Italy. Methods: Data were collected using an anonymous self-administered questionnaire from April to November 2023, targeting parents in p ..read more

Vaccines, Vol. 12, Pages 419: The Memory-CD8+-T-Cell Response to Conserved Influenza Virus Epitopes in Mice Is Not Influenced by Time since Previous Infection Vaccines doi: 10.3390/vaccines12040419 Authors: Lanfermeijer van de Ven Hendriks van Dijken Lenz Vos Borghans van Baarle de Jonge To protect older adults against influenza A virus (IAV) infection, innovative strategies are imperative to overcome the decrease in protective immune response with age. One approach involves the boosting of CD8+ T cells at middle age that were previously induced by natural infection. At this stage, the immune ..read more

Vaccines, Vol. 12, Pages 410: Nanocapsules Comprised of Purified Protein: Construction and Applications in Vaccine Research Vaccines doi: 10.3390/vaccines12040410 Authors: Ivana Skakic Aya C. Taki Jasmine E. Francis Chaitali Dekiwadia Thi Thu Hao Van Carina C. D. Joe Tram Phan George Lovrecz Paul R. Gorry Paul A. Ramsland Anna K. Walduck Peter M. Smooker Nanoparticles show great promise as a platform for developing vaccines for the prevention of infectious disease. We have been investigating a method whereby nanocapsules can be formulated from protein, such that the final capsules contain only ..read more

Vaccines, Vol. 12, Pages 409: Design and Characterization of a New Formulation for the Delivery of COVID-19-mRNA Vaccine to the Nasal Mucosa Vaccines doi: 10.3390/vaccines12040409 Authors: Ayça Altay Benetti Eugene Yang Zhi Tan Zi Wei Chang Ki Hyun Bae Ma Thinzar Thwin Ram Pravin Kumar Muthuramalingam Kuo-Chieh Liao Yue Wan Lisa F. P. Ng Laurent Renia Jianping Liu Xiaoyuan Chen Yi Yan Yang Kevin P. White Giorgia Pastorin Chitosan, a natural polysaccharide derived from chitin, possesses biocompatibility, biodegradability, and mucoadhesive characteristics, making it an attractive material for th ..read more

Vaccines, Vol. 12, Pages 411: Lineage Replacement and Genetic Changes of Four HR-HPV Types during the Period of Vaccine Coverage: A Six-Year Retrospective Study in Eastern China Vaccines doi: 10.3390/vaccines12040411 Authors: Wenjie Qu Chen Hua Yaping Wang Yan Wang Lu Zhang Zhiheng Wang Wenqian Shi Fang Chen Zhiyong Wu Qian Wang Lu Lu Shibo Jiang Long Sui Yanyun Li Objective: This study aimed to provide clinical evidence for lineage replacement and genetic changes of High-Risk Human Papillomavirus (HR-HPV) during the period of vaccine coverage and characterize those changes in eastern China. M ..read more

Vaccines, Vol. 12, Pages 412: Bacterium-like Particles from Corynebacterium pseudodiphtheriticum as Mucosal Adjuvant for the Development of Pneumococcal Vaccines Vaccines doi: 10.3390/vaccines12040412 Authors: Ramiro Ortiz Moyano Fernanda Raya Tonetti Mariano Elean Yoshiya Imamura Kohtaro Fukuyama Yoshihito Suda Vyacheslav Melnikov Alexander Suvorov María Guadalupe Vizoso-Pinto Haruki Kitazawa Julio Villena Previously, it was shown that intranasally (i.n.) administered Corynebacterium pseudodiphtheriticum 090104 (Cp) or CP-derived bacterium-like particles (BLPs) improve the immunogenicity of t ..read more