Hi there, I've been interested in studying the DNA of ancient civilizations, like understanding my ancestry, etc. I've encountered many data and terms like steppe, Neolithic Iranian, etc., but couldn't comprehend much. I want to start from basics. Where should I begin? My qualifications: high school (12th grade) with science (biology). btw, I've studied genetics in grade 12th (in biology textbook by NCERTs) submitted by /u/oaExist [visit reddit] [comments ..read more

I'm writing a Research proposal to apply for PhD in Human Genetics and Genomics. Out of the few ideas I had I'm currently researching abt intronic regulation of DMD. Do I need to write a proposal relevant to the interests of the PI or university I'm applying to or can the same proposal be used for every uni? submitted by /u/Mendelianne [visit reddit] [comments ..read more

I Need a Study (or a very official source) proving that Double Chin / Submental Fullness / Submental Fat is Hereditary / Genetic submitted by /u/fac11111 [visit reddit] [comments ..read more

I'm a third year undergrad studying plant science with a minor in genetics. I've been in a cotton genomics research lab for the past three years and absolutely love it. So much that I decided I want to go into research and pursue a PhD. My GPA isn't where it needs to be (2.6), and after my rough semester I see it tanking more. If I drop my minor I can graduate on time, but if I keep it I'll be a year behind. My major doesn't require all the chem and biochem classes needed for the minor, but I'm scared I can't get into grad school without it. Does anyone have advice for my situation? I'm sinki ..read more

submitted by /u/Pretend_Paramedic_10 [visit reddit] [comments ..read more

Hello everyone, I have a question: how can I distinguish or determine whether a genetic variant (f.e. WES) seen on IGV is heterozygous, mosaic, or a PCR duplicate? submitted by /u/ExtremeGenetics700 [visit reddit] [comments ..read more

I have a question I'm hoping some of you bright minds can help with. In reviewing DNA sequencing data, if a person shows a deletion of shank3 at 22q.13.33 and it is also AD, is that definitive information for that person to have 22q13 deletion syndrom / phelan mcdermid? Are there other potentially protective genes that would make that deletion unremarkable or other genes that would 'neutralize' the effects of that deletion? I guess I'm asking is there anything else to look at DNA wise in order to be able to come to a positive determination of that individual having that deletion syndrome? The ..read more

Hi y'all, I'm new to the C. elegans model, and I was wondering what genetic tools can be used. When I worked with E. coli, we would use electroporation to insert a plasmid into the cells to express a gene. In rodents, sometimes rAAV is used. What would be the equivalent for C. elegans? Essentially, could I use rAAV to insert something like a gene construct that contained GFP with a specific promoter into C. elegans? (The construct I have in mind already exists and is used congenitally in a mutant strain, I was just wondering if it can be delivered via rAAV or something similar). submitted by ..read more

I am doing a project on ceramic dog effigies from Pre-Columbian West Mexican shaft tombs. One of these statues appears to depict a pair of conjoined dogs, can dogs actually be born and survive as conjoined twins? submitted by /u/nonbearingwall [visit reddit] [comments ..read more

submitted by /u/TheMuseumOfScience [visit reddit] [comments ..read more