Clinical factors associated with patterns of endocrine therapy adherence in premenopausal breast cancer patients
BMC » Breast Cancer Research
by Kirsten M. Woolpert, Julie A. Schmidt, Thomas P. Ahern, Cathrine F. Hjorth, Dóra K. Farkas, Bent Ejlertsen, Lindsay J. Collin, Timothy L. Lash and Deirdre P. Cronin-Fenton
3d ago
Patients with hormone receptor positive breast cancer are recommended at least five years of adjuvant endocrine therapy, but adherence to this treatment is often suboptimal. We investigated longitudinal trends ..read more
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Paradoxical cancer cell proliferation after FGFR inhibition through decreased p21 signaling in FGFR1-amplified breast cancer cells
BMC » Breast Cancer Research
by Feng Chi, Jason I. Griffiths, Aritro Nath and Andrea H. Bild
1w ago
Fibroblast growth factors (FGFs) control various cellular functions through fibroblast growth factor receptor (FGFR) activation, including proliferation, differentiation, migration, and survival. FGFR amplific ..read more
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Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancer
BMC » Breast Cancer Research
by Michael U J Oliphant, Dipikaa Akshinthala and Senthil K. Muthuswamy
1w ago
Patient-derived organoid models of estrogen receptor-positive (ER+) breast cancer would provide a much-needed tool to understand drug resistance and disease progression better. However, the establishment and l ..read more
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Factors associated with overall survival in breast cancer patients with leptomeningeal disease (LMD): a single institutional retrospective review
BMC » Breast Cancer Research
by Gerald Wallace, Ronak Kundalia, Ethan Vallebuona, Biwei Cao, Youngchul Kim, Peter Forsyth, Aixa Soyano, Inna Smalley and Yolanda Pina
1w ago
Breast cancer-related leptomeningeal disease (BC-LMD) is a dire diagnosis for 5–8% of patients with breast cancer (BC). We conducted a retrospective review of BC-LMD patients diagnosed at Moffitt Cancer Center ..read more
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Temporal changes in mammographic breast density and breast cancer risk among women with benign breast disease
BMC » Breast Cancer Research
by Maeve Mullooly, Shaoqi Fan, Ruth M. Pfeiffer, Erin Aiello Bowles, Máire A. Duggan, Roni T. Falk, Kathryn Richert-Boe, Andrew G. Glass, Teresa M. Kimes, Jonine D. Figueroa, Thomas E. Rohan, Mustapha Abubakar and Gretchen L. Gierach
2w ago
Benign breast disease (BBD) and high mammographic breast density (MBD) are prevalent and independent risk factors for invasive breast cancer. It has been suggested that temporal changes in MBD may impact futur ..read more
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Correction: The novel phosphatase NUDT5 is a critical regulator of triple-negative breast cancer growth
BMC » Breast Cancer Research
by Jing Qian, Yanxia Ma, William M. Tahaney, Cassandra L. Moyer, Amanda Lanier, Jamal Hill, Darian Coleman, Negar Koupaei, Susan G. Hilsenbeck, Michelle I. Savage, Brent D. G. Page, Abhijit Mazumdar and Powel H. Brown
2w ago
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BIRC5 expression by race, age and clinical factors in breast cancer patients
BMC » Breast Cancer Research
by Alina M. Hamilton, Andrea Walens, Sarah C. Van Alsten, Linnea T. Olsson, Joseph Nsonwu-Farley, Xiaohua Gao, Erin L. Kirk, Charles M. Perou, Lisa A. Carey, Melissa A. Troester and Yara Abdou
3w ago
Survivin/BIRC5 is a proliferation marker that is associated with poor prognosis in breast cancer and an attractive therapeutic target. However, BIRC5 has not been well studied among racially diverse population ..read more
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Factors associated with engraftment success of patient-derived xenografts of breast cancer
BMC » Breast Cancer Research
by Jongwon Lee, GunHee Lee, Hye Seon Park, Byung-Kwan Jeong, Gyungyub Gong, Jae Ho Jeong and Hee Jin Lee
3w ago
Patient-derived xenograft (PDX) models serve as a valuable tool for the preclinical evaluation of novel therapies. They closely replicate the genetic, phenotypic, and histopathological characteristics of prima ..read more
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TMEM120B strengthens breast cancer cell stemness and accelerates chemotherapy resistance via β1-integrin/FAK-TAZ-mTOR signaling axis by binding to MYH9
BMC » Breast Cancer Research
by Ran Hu, Yu Cao, Yuanyuan Wang, Tingting Zhao, Kaibo Yang, Mingwei Fan, Mengyao Guan, Yuekang Hou, Jiao Ying, Xiaowen Ma, Ning Deng, Xun Sun, Yong Zhang and Xiupeng Zhang
3w ago
Breast cancer stem cell (CSC) expansion results in tumor progression and chemoresistance; however, the modulation of CSC pluripotency remains unexplored. Transmembrane protein 120B (TMEM120B) is a newly discov ..read more
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Breast cancer survivors suffering from lymphedema: What really do affect to corporeality/body image? A qualitative study
BMC » Breast Cancer Research
by Laura González-Fernández, Carlos Romero-Morales, Beatriz Martínez-Pascual, Angela Río-González, Ester Cerezo-Téllez and Inmaculada López-Martín
3w ago
Breast cancer-related lymphedema is currently one of the most serious complications that most affect the quality of life of women undergoing breast cancer. The aim of this study was to explore in-depth the exp ..read more
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