Do not be anxious …
Let Life Happen
by Barbara Jacoby
1d ago
Do not be anxious about anything, but in every situation, by prayer and petition, with thanksgiving, present your requests to God. And the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus. – Philippians 4:6-7 The post Do not be anxious … appeared first on Let Life Happen ..read more
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Justin Trogdon, PhD, on Sequencing Single-Agent Chemo in Metastatic Cancer
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by Barbara Jacoby
1d ago
By: Jeff Minerd From: medpagetoday.com A cost-effectiveness study provided guidance on optimal treatment sequencing of single-agent chemotherapy options for women with metastatic breast cancer. “In this setting where multiple single-agent chemotherapy options are recommended by clinical guidelines and share similar survival and adverse event trajectories, treatment sequencing approaches that minimize costs early may improve the value of care,” said Stephanie B. Wheeler, PhD, MPH, of the Gillings School of Global Public Health at the University of North Carolina (UNC) at Chapel Hill, and collea ..read more
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Every great achiever …
Let Life Happen
by Barbara Jacoby
2d ago
“Every great achiever is inspired by a great mentor.” – Lailah Gifty Akita, Think Great: Be Great! The post Every great achiever … appeared first on Let Life Happen ..read more
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Could a Cardiac Drug Stop Breast Cancer Metastasis?
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by Barbara Jacoby
2d ago
By: Kara Baskin From: tufts.edu riple-negative breast cancer is notoriously hard to treat. Assistant Professor Madeleine Oudin’s lab at the School of Engineering studies how to tame those cancer cells into submission. With Laidlaw Scholar Deepti Srinivasan, a senior biomedical engineering major and an aspiring physician, Oudin investigated how manipulating potassium channel activity could alter those cells’ bioelectric signals—making the cancer less likely to spread. In the process, they determined that an FDA-approved anti-arrythmia drug, amiodarone, could alter cells in the same w ..read more
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Breast Cancer and the Loss From Self-Sacrifice
Let Life Happen
by Barbara Jacoby
3d ago
From my perspective, women often put themselves in positions of self-sacrifice in order to accommodate the needs of everyone else around them. It becomes easy to do so because of the satisfaction in knowing that as a result of what you have done has improve the situation of others is rewarding in and of itself. Take for example the mother who makes sure that her family is fed even when there is not enough food for her to eat. Or the wife who is being abused who does nothing to protect herself because the lack of conflict will usually diffuse an abuser. So what happens when a woman sacrifices t ..read more
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Whatever the goal …
Let Life Happen
by Barbara Jacoby
3d ago
Whatever the goal, small, daily investments can bring big results. – Michael Hyatt, Living Forward: A Proven Plan to Stop Drifting and Get the Life You Want The post Whatever the goal … appeared first on Let Life Happen ..read more
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FDA Grants Fast Track Designation to CFI-402257 for ER+/HER2– Breast Cancer
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by Barbara Jacoby
3d ago
By: Chris Ryan From: onclive.com The FDA has granted a fast track designation to best-in-class threonine tyrosine kinase (TTK) inhibitor CFI-402257, both as monotherapy and in combination with fulvestrant (Faslodex), for the treatment of adult patients with estrogen receptor (ER)–positive/HER2-negative advanced breast cancer after disease progression on prior CDK4/6 inhibitors and endocrine therapy.1 TTK, which is correlated with high grade in tumors and poor patient outcomes, is upregulated in several cancers. Preclinical models showed that treatment with CFI-402257 suppressed tumor growth i ..read more
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The heart in …
Let Life Happen
by Barbara Jacoby
4d ago
“The heart in every human is the sacred love.” – Lailah Gifty Akita, Pearls of Wisdom: Great mind The post The heart in … appeared first on Let Life Happen ..read more
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Updates in the Treatment of Early-stage HR+ Breast Cancer
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by Barbara Jacoby
4d ago
By: Charles Geyer From: onclive.com Two breast cancer experts review updates from the SOFT and TAILORx trials and discuss racial disparities in breast cancer treatment and clinical trials. Dr. Ian Krop: So, kind of keeping with this theme of how we personalize therapy, we had in the adjuvant setting, we had this – I thought it was an interesting analysis of the SOFT data, speaking of ovarian suppression. In terms of looking at this genomic marker, the breast cancer index, which looks at two genes that have been associated with response to endocrine therapy, also looking at molecular grade, and ..read more
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Deep pain …
Let Life Happen
by Barbara Jacoby
5d ago
“Deep pain awakens the pleasure of wonder.” – Lailah Gifty Akita The post Deep pain … appeared first on Let Life Happen ..read more
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