The Alzheimer's Disease Assessment Scale-Cognitive Subscale test is one of the most frequently used tests to measure cognition in research studies and clinical trials for new drugs and other interventions. It's more thorough than the Mini Mental State Exam, and it primarily measures language and memory. The ADAS-Cog consists of 11 parts and takes approximately 30 minutes to administer. The ADAS-Cog was developed as a two-part scale: one that measured cognitive functions and one that measured non-cognitive functions such as mood and behavior. Most current research uses the ..read more

  Fall prevention is key to protecting the health, safety, and life longevity of your loved one, especially if they are living with Alzheimer’s or any other form of dementia. Nymbl offers balance training tools, fall risk assessments, digital balance screenings, and other resources to improve balance, prevent falls, and improve independence. A short initial assessment helps customize plans with exercises and activities tailored to the user’s needs and abilities. Nymbl also offers fun brain games to help sharpen cognitive function and keep users mentally engaged — both important aspects mi ..read more

  A “chaperone” molecule that slows the formation of certain proteins reversed disease signs, including memory impairment, in a mouse model of Alzheimer’s disease, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.   In the study, published in Aging Biology, researchers examined the effects of a compound called 4-phenylbutyrate (PBA), a fatty-acid molecule known to work as a “chemical chaperone” that inhibits protein accumulation. In mice that model Alzheimer’s disease, injections of PBA helped to restore signs of normal prot ..read more

  Limbic-predominant age-related TDP-43 encephalopathy (or LATE-NC) is the most recently identified form of dementia, noted for its close similarity to Alzheimer’s. Overview According to a study published in Brain, a Journal of Neurology, on April 30, 2019, researchers have linked a protein called TDP-43 to a newly identified form of dementia: Limbic-predominant age-related TDP-43 encephalopathy (LATE-NC). Risks Factors LATE usually affects older individuals, particularly those over age 80. Although advancing age is a risk factor for LATE, dementia is not part of the typical a ..read more

  The history of prosecuting individuals with dementia and other mental illnesses is complex and has evolved over time. The treatment of individuals with mental illnesses in legal contexts has seen significant changes, reflecting shifts in societal attitudes, medical understanding, and legal frameworks. Ancient and Medieval Time In ancient civilizations, such as Mesopotamia and Greece, there was limited understanding of mental illnesses. Individuals with severe mental disorders were often viewed as possessed by evil spirits or as outcasts. Punitive measures, including imprisonment, tortur ..read more

  Etymology of Dementia The word "dementia" has its origins in Latin and can be traced back to ancient Roman medical texts. Perhaps the earliest record of a dementia syndrome originated in ancient Egypt in about 3,000 BC, when Prince Ptah-Hotep mentioned senile deterioration, which for the time was a consequential natural landmark in the process of human aging. But the world dementia appeared first in the record of mankind in around 600 A.D. Saint Isidore (560–636 A.D.), the archbishop of Seville, used the term ‘dementia’ for the first time in his book, ‘Etymologies’. The term "dementia ..read more

  The history of Alzheimer's research spans over a century, characterized by significant milestones in understanding the disease's causes, symptoms, diagnosis, and treatment. Here's an overview of key events in Alzheimer's research history: 1.       Early 20th Century: Discovery of Alzheimer's Disease ·         In 1906, German psychiatrist and neurologist Alois Alzheimer identified a new neurological disorder in a patient named Auguste Deter. He presented his findings at a medical conference, describing the patient's sy ..read more

  Nature can have numerous positive effects on individuals with Alzheimer's disease. Whether it's spending time in a park, garden, forest, or any natural setting, exposure to nature can offer therapeutic benefits and enhance the overall well-being of those with Alzheimer's. But people, living at or near the large water sources, like ocean, sea, or a lake, have an extra benefits, as the patients may enjoy the so-called beach therapy. Beach therapy, also known as beach-based or coastal therapy, can offer several benefits for individuals with Alzheimer's disease. The calming and sensory-ri ..read more

  Kamaria was 28 years old when her mother, Mary, was diagnosed with early-onset Alzheimer's disease. It had only been five years since Kamaria had lost her father to a brain tumor and stopped being his primary caretaker. It had only been five years since Kamaria had lost her father to a brain tumor and stopped being his primary caretaker. One night, during the journey to diagnosis, Kamaria went out with a friend and broke down crying at the unfairness of it all. But those were the only tears she allowed herself. "After I had my feelings about it, it was trying to figure out, how do ..read more

  What is MindMate?   MindMate is a Desktop application designed to support and improve cognitive function and mental well-being, particularly for older adults. It offers a range of brain-training games, puzzles, and exercises that stimulate memory, attention, problem-solving skills, and overall cognitive abilities. The app was initially developed to cater to individuals with dementia or Alzheimer's disease, as it aims to slow down cognitive decline and maintain mental sharpness. It provides a variety of interactive activities and challenges designed to engage users and promote brain ..read more