Ovarian Cancer Research Foundation announces $2.4 million in new funding
Oncology News Australia » Ovarian Cancer
by ONA Editor
6d ago
Today, three ovarian cancer research institutions have received significant funding from the Ovarian Cancer Research Foundation (OCRF) through their annual National Research Grants Scheme. Totalling over $2 million, the grants will enable Australian researchers to investigate solutions across ovarian cancer diagnostics and treatment, with the aim to improve patient outcomes today and long-term survival rates ..read more
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Ovarian cancer: Targeting LTA4H improves the tumour immune microenvironment
Oncology News Australia » Ovarian Cancer
by ONA Editor
1w ago
In ovarian cancer, the abnormal expression of various metabolic enzymes in the metabolism of polyunsaturated fatty acids (PUFA) is involved in the development of tumours and immune regulation. Most of the patients are admitted with advanced disease, due to the hidden symptoms and difficulty in detecting at early stage. The chemoresistance to standard platinum-based chemotherapy ..read more
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Researchers develop test that could identify precancerous lesions on the fallopian tubes
Oncology News Australia » Ovarian Cancer
by ONA Editor
1w ago
Researchers at the Johns Hopkins Kimmel Cancer Center and the Department of Gynecology and Obstetrics at the Johns Hopkins University School of Medicine, USA, have developed an algorithm to identify high-risk precancerous lesions on the fallopian tubes. Known as serous tubal intraepithelial carcinomas (STICs), these lesions are thought to be the main precursors of ovarian ..read more
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BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula
Oncology News Australia » Ovarian Cancer
by ONA Editor
2w ago
A new research paper was published in Oncotarget‘s Volume 15 on February 22, 2024, entitled, “Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health.” In this new exploratory and descriptive study, researchers from Vito Fazzi Hospital, University of Salento, Strategic Regional ..read more
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Research identifies predictor of outcomes, chemoresistance for ovarian cancer patients
Oncology News Australia » Ovarian Cancer
by ONA Editor
3w ago
In a major scientific breakthrough, newly published research from an international consortium led by the University of Minnesota’s Masonic Cancer Center, USA, has the potential to transform the landscape of ovarian cancer treatment. Published today in JAMA Network Open, the findings indicate that ovarian cancer patients with high levels of stroma within their tumours are twice as ..read more
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Elenagen delays disease progression
Oncology News Australia » Ovarian Cancer
by ONA Editor
1M ago
CureLab Oncology, a clinical-stage, pre-IPO biotech company, announced that its novel biological agent, Elenagen, has been shown to significantly enhance standard chemotherapy and provides clinical benefits for the patients with the deadliest form ovarian cancer. Elenagen belongs to a novel class of biological agents, supercoiled circular DNA (plasmids). The study, published in Frontiers in Oncology, shows that ..read more
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Outsmarting chemo-resistant ovarian cancer
Oncology News Australia » Ovarian Cancer
by ONA Editor
1M ago
Women diagnosed with ovarian cancer may initially respond well to chemotherapy, but the majority of them will develop resistance to treatment and die from the disease. Now Northwestern Medicine scientists have discovered the Achilles heel of chemotherapy-resistant ovarian cancer — its hunger for cholesterol — and how to sneakily use that to destroy it. In ..read more
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Researchers leverage AI to develop early diagnostic test for ovarian cancer
Oncology News Australia » Ovarian Cancer
by ONA Editor
1M ago
For over three decades, a highly accurate early diagnostic test for ovarian cancer has eluded physicians. Now, scientists in the Georgia Tech Integrated Cancer Research Center (ICRC) have combined machine learning with information on blood metabolites to develop a new test able to detect ovarian cancer with 93 percent accuracy among samples from the team’s study group ..read more
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MRNA therapeutic successfully combats ovarian cancer in mice
Oncology News Australia » Ovarian Cancer
by ONA Editor
1M ago
Each year, several thousand women in Germany die from ovarian cancer. In many cases, the disease is only detected when it is very advanced and metastases have already formed – usually in the intestines, abdomen or lymph nodes. At such a late stage, only 20 to 30 percent of all those affected survive the next ..read more
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Ageing in cells may boost ovarian cancer spread
Oncology News Australia » Ovarian Cancer
by ONA Editor
1M ago
Ovarian cancer is dangerous because it often goes undetected until it has spread beyond the ovaries, and the symptoms can also be attributed to other conditions. Scientists believe that ageing can increase the spread of ovarian and other cancers, but the underlying mechanisms are not fully clear. Now, researchers at the Indian Institute of Science (IISc) have found that ..read more
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