Introduction and U.K.’s exit from the EU On leaving the EU, EU-REACH legislation was copied over into UK-REACH as of 01 January 2020. Applying to only England, Wales and Scotland (collectively referred to as Great Britain or GB), Northern Ireland continues to be regulated by EU-REACH. The UK-REACH transitional arrangements … The post UK-REACH Planning appeared first on Insights From Our Labs to Yours ..read more

When it comes to designing clinical trials with expedience and efficiency, many drug developers are choosing biomarker-driven strategies for their investigational precision medicines. As key features of developing new therapies and diagnostics, biomarkers define the disease biology, provide potential targets for new therapies and provide strong potential for market differentiation. … The post Top considerations for developing a biomarker solution and CDx strategy appeared first on Insights From Our Labs to Yours ..read more

The European Chemicals Agency (ECHA) recently conducted a review project regarding the design of the OECD 443 (Extended One-Generation Reproductive Toxicity Study, or EOGRTS). The project’s goal was to assess the performance of the study in terms of study design, conduct and findings to determine if the study design currently … The post How to de-risk OECD 443 studies through optimized dose level selections appeared first on Insights From Our Labs to Yours ..read more

Every clinical trial relies on data from its study participants to inform decisions regarding the safety and efficacy of a potential new treatment. Clinical trial sponsors rely on the data from laboratory tests to bring clear insights that advance studies. Labcorp Central Laboratory Services generates more clinical trial data than … The post What does a central lab do? 4 core services to know appeared first on Insights From Our Labs to Yours ..read more

There is pressure worldwide for better, faster access to biological alternatives to conventional crop protection chemicals (CPCs). The U.S. Environmental Protection Agency (EPA) is ahead of regions such as the European Union (EU) in revising its regulatory approaches for biopesticides and in having a division dedicated to them, namely, the … The post Faster access to biopesticide alternatives to conventional pesticides under the U.S. BPPD regulatory framework appeared first on Insights From Our Labs to Yours ..read more

The association of excessive alcohol consumption and liver disease is well documented. The effect on levels of alcohol consumption during the COVID-19 pandemic has more recently been investigated, Julien et al., (Hepatology 2022, Vol 75, Issue 6, 1480-1490) estimated that the one-year increase in alcohol consumption during the pandemic would … The post Alcohol-related liver disease: Inherent Challenges and Strategies for Successful Clinical Trial Conduct appeared first on Insights From Our Labs to Yours ..read more

When it comes to discoveries in oncology, cancer patients can’t wait, which means neither can you. At Labcorp Preclinical Oncology, we understand there are many steps, phases and regulations to wade through to get to a lead drug candidate—all while time is of the utmost importance. We are excited to … The post Program management services are now offered as part of Labcorp’s Preclinical Oncology Services appeared first on Insights From Our Labs to Yours ..read more

March is National Kidney Month, and we at Labcorp are committed to improving the renal health of patients worldwide. The field of nephrology clinical research has been steadily adding new interventional trials over the last five years at an average pace of 176 trials per year. This activity reflects the … The post Enabling better access to kidney disease trials appeared first on Insights From Our Labs to Yours ..read more

In December 2022, Labcorp and Biomakers signed an agreement that will positively impact thousands of cancer patients in Latin America through greater access to diagnostic molecular profiling and participation in clinical trials. We recently asked Nicolas Kirchuk (NK), CEO and co-founder of Biomakers, and Isagani Chico (IC), MD, VP, global … The post Innovative collaboration between Biomakers and Labcorp to provide greater access to oncology patients in Latin America appeared first on Insights From Our Labs to Yours ..read more

The news broke with an ominous headline: “Blots on a Field?” Superimposed over an eerie image of a scientist lit by the green glow of a light-box, was the phrase “image sleuth finds signs of fabrication in scores of Alzheimer’s articles, threatening a reigning theory of the disease.”1 This story … The post The true impact of alleged fraud on Alzheimer’s research appeared first on Insights From Our Labs to Yours ..read more