People with multiple sclerosis (MS) who start treatment with a mild-to-moderate efficacy disease-modifying therapy (DMT) were more likely to switch to another DMT, an analysis of the German MS Registry finds. Starting a DMT between 2014 and 2017 was also a predictor of switching. Disease activity despite treatment was the most common reason to change […] The post Use of mild-to-moderate DMTs predicts switching to other DMTs appeared first on Multiple Sclerosis News Today ..read more

Alternative splicing, a biological process that allows a single gene to code for multiple proteins, is extensively disrupted in immune cells isolated from untreated multiple sclerosis (MS) patients, and long-term treatment with interferon beta-based therapies largely corrects the defects, a study found. “Alternative splicing is a potential biomarker warning of disease activity and for predicting […] The post Interferon beta corrects gene processing disrupted in MS: Study appeared first on Multiple Sclerosis News Today ..read more

A small molecule called ESI1 stimulated the repair of the myelin sheath, the fatty coating on nerve fibers that is damaged in multiple sclerosis (MS), a study found. In an MS mouse model, this resulted in improved motor function and nerve cell communication, as well as reduced signs of disease-driving inflammation. ESI1 also enhanced myelin […] The post Small molecule promotes myelin sheath repair in MS mice: Study appeared first on Multiple Sclerosis News Today ..read more

Is there something you now have that you once hoped and prayed for? I’ve been struggling with the demands of a new job for the past few weeks. As a virtual dietitian, I heavily rely on computers to meet with clients and do other necessary work. But staring at a computer screen for up to […] The post Recent vision problems with MS remind me to focus on my progress appeared first on Multiple Sclerosis News Today ..read more

Alexander Gow, PhD, a professor at Wayne State University School of Medicine in Detroit, has been awarded a grant to study how stressed oligodendrocytes, the cells that produce myelin in the brain and spinal cord, could be at the origin of multiple sclerosis (MS). The three-year, $644,827 grant from the National MS Society will support […] The post Wayne State professor wins grant to study oligodendrocytes in MS appeared first on Multiple Sclerosis News Today ..read more

The National Multiple Sclerosis Society has awarded Inflectis BioScience a grant valued at $649,601 to advance the preclinical development of IFB-048, the company’s experimental treatment to promote myelin repair in multiple sclerosis (MS). “This grant along with the support from the Society are a testimony to the potential of IFB-048 in multiple sclerosis,” Pierre Miniou, […] The post Nearly $650k awarded to advance potential remyelination drug IFB-048 appeared first on Multiple Sclerosis News Today ..read more

I feel like I’ve been in this exact place, saying exactly what I’m saying right now. Have I done this in a past life? Did I dream it and am now subconsciously acting it out in reality? Or is my brain performing a fact-check on its memory system and signaling it with the sensation known […] The post There’s comfort in putting a name to a multiple sclerosis symptom appeared first on Multiple Sclerosis News Today ..read more

Among immigrants to Canada, the risk of multiple sclerosis (MS) is higher for those who have spent a greater portion of their life in Canada, a new study reports. The study, “Proportion of Life Spent in Canada and the Incidence of Multiple Sclerosis in Permanent Immigrants,” was published in Neurology. In wealthy countries such as […] The post Immigrants to Canada see MS risk rising with time in country: Study appeared first on Multiple Sclerosis News Today ..read more

Canada has one of the world’s highest rates of multiple sclerosis (MS) in the world, and this month residents are being urged to come together to raise awareness of and funds for people affected by the neurodegenerative disorder. May is Multiple Sclerosis Awareness Month in Canada, and MS Canada is inviting supporters to participate in any […] The post MS Canada seeks nationwide participation in awareness month appeared first on Multiple Sclerosis News Today ..read more

What’s a reliable way to wreck your mood? Fighting your circadian rhythms. I’m a recovering night owl. I used to get more done between 10 p.m. and 2 a.m. than I did in the other 20 hours of the day. I routinely studied past 2 a.m. during college and medical school, cramming in massive amounts […] The post Why we should go with the flow of our biological clocks appeared first on Multiple Sclerosis News Today ..read more