Studies Assess Impact of Cancer Risk-Reduction Measures for People with BRCA Changes
Cancer Currents
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12h ago
For people with inherited changes in the BRCA1 or BRCA2 genes, regular MRI scans and undergoing a surgery called a salpingo-oophorectomy appear to lower their chances of dying from breast and ovarian cancer, according to results from two studies ..read more
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New on NCI’s Websites for April 2024
Cancer Currents
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3d ago
NCI periodically provides updates on new websites and other online content of interest to the cancer community. See selected content that has been added as of April 2024 ..read more
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Drug Combination May Have Potential for Cancers with TP53 Mutations
Cancer Currents
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1w ago
Although TP53 mutations help drive the growth of most cancers, there are no FDA-approved therapies that target altered p53 proteins. Now a drug combination has shown promise in mice and is being tested in a clinical trial ..read more
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Rusfertide Nearly Eliminates Need for Phlebotomies to Treat Polycythemia Vera
Cancer Currents
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2w ago
Adding rusfertide to treatment for polycythemia vera cut phlebotomy rates from nine to less than one per year in a recent clinical trial. The finding may improve the quality of life for those who manage the blood cancer with frequent blood draws ..read more
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Simple Hysterectomy May Expand Treatment Options for Early-Stage Cervical Cancer
Cancer Currents
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2w ago
For some people with early-stage cervical cancer, a surgical procedure called a simple hysterectomy may be a safe and effective alternative to treatment with a radical hysterectomy, results from the SHAPE trial show ..read more
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Stealing Strategies from Cancerous T Cells May Boost Immunotherapy
Cancer Currents
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3w ago
Adding a fusion of parts of two genes helped engineered T cells divide faster, kill more tumor cells, and survive longer in mice without making the T cells behave like cancer cells ..read more
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Nivolumab Injections Could Make Treatment Easier for More People with Cancer
Cancer Currents
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1M ago
In a clinical trial, an injectable form of nivolumab (Opdivo) was as effective against kidney cancer as the intravenous form of the drug. Side effects were also similar and treatment time was shorter. Injectable immunotherapies, several experts said, if found to be comparable to IV forms, can be more convenient to receive and accessible to more people ..read more
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Lutathera Shows Promise as Part of Initial Therapy for Some Neuroendocrine Tumors
Cancer Currents
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1M ago
Adding Lu 177-dotate to the initial treatment of certain advanced neuroendocrine tumors nearly tripling the length of time people survive without their tumors getting worse, according to new clinical trial results ..read more
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CtDNA May Guide Who Needs Chemo After Colorectal Cancer Surgery
Cancer Currents
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1M ago
Results from a new study suggest that the presence of circulating tumor DNA (ctDNA) in blood samples can predict which patients with colorectal cancer should and shouldn’t get chemotherapy after surgery to remove their tumors ..read more
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Pump Up the Volume: “Priming Agents” May Improve Cancer Liquid Biopsies
Cancer Currents
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1M ago
Using two different techniques, researchers showed they could temporarily boost ctDNA levels in the blood of mice with tumors. With more ctDNA in collected blood draws, a liquid biopsy could better detect cancer, the research team found ..read more
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