FDA Approves Trastuzumab Deruxtecan for Any HER2-Positive Solid Cancer
Cancer Currents
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23h ago
Trastuzumab deruxtecan (Enhertu) can now be used to treat any advanced solid cancer that produces high levels of the protein HER2 (HER2-positive tumors). FDA’s accelerated approval was based on findings from three clinical trials ..read more
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Q&A: Learning About the Cancer Care Challenges LGBTQ+ People Face
Cancer Currents
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23h ago
Gwendolyn Quinn, Ph.D., a health psychologist at NYU Langone Health Perlmutter Cancer Center, discusses the challenges faced by sexual and gender minority people being treated for cancer and ways to address them ..read more
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Approval of Elahere Expands Treatment Options for Some Advanced Ovarian Cancers
Cancer Currents
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1w ago
FDA approved mirvetuximab soravtansine-gynx (Elahere) to treat people with advanced, platinum-resistant ovarian cancer whose tumors overproduce a protein called FR-α. The full approval was based on the results of a large, randomized trial called MIRASOL, which showed Elahere improved survival for these people ..read more
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Scientists Link a Single Type of Bacteria to Colorectal Cancer
Cancer Currents
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2w ago
NCI-funded researchers have pinpointed a single type of the bacterium F. nucleatum that appears to fuel the development and growth of colorectal cancer. In mice, the bacterium, Fna C2, appeared to cause more adenomas to form in the large intestine and it was often found in human tumor samples ..read more
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Studies Assess Impact of Cancer Risk-Reduction Measures for People with BRCA Changes
Cancer Currents
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2w ago
For people with inherited changes in the BRCA1 or BRCA2 genes, regular MRI scans and undergoing a surgery called a salpingo-oophorectomy appear to lower their chances of dying from breast and ovarian cancer, according to results from two studies ..read more
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New on NCI’s Websites for April 2024
Cancer Currents
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3w ago
NCI periodically provides updates on new websites and other online content of interest to the cancer community. See selected content that has been added as of April 2024 ..read more
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Drug Combination May Have Potential for Cancers with TP53 Mutations
Cancer Currents
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1M ago
Although TP53 mutations help drive the growth of most cancers, there are no FDA-approved therapies that target altered p53 proteins. Now a drug combination has shown promise in mice and is being tested in a clinical trial ..read more
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Rusfertide Nearly Eliminates Need for Phlebotomies to Treat Polycythemia Vera
Cancer Currents
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1M ago
Adding rusfertide to treatment for polycythemia vera cut phlebotomy rates from nine to less than one per year in a recent clinical trial. The finding may improve the quality of life for those who manage the blood cancer with frequent blood draws ..read more
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Simple Hysterectomy May Expand Treatment Options for Early-Stage Cervical Cancer
Cancer Currents
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1M ago
For some people with early-stage cervical cancer, a surgical procedure called a simple hysterectomy may be a safe and effective alternative to treatment with a radical hysterectomy, results from the SHAPE trial show ..read more
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Stealing Strategies from Cancerous T Cells May Boost Immunotherapy
Cancer Currents
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1M ago
Adding a fusion of parts of two genes helped engineered T cells divide faster, kill more tumor cells, and survive longer in mice without making the T cells behave like cancer cells ..read more
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