Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts | Science
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50m ago
Organisms exhibit extensive variation in ecological niche breadth, from very narrow (specialists) to very broad (generalists). Two general paradigms have been proposed to explain this variation: (i) trade-offs between performance efficiency and breadth ..read more
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Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules | Science
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50m ago
Tubulin, one of the most abundant cytoskeletal building blocks, has numerous isotypes in metazoans encoded by different conserved genes. Whether these distinct isotypes form cell type– and context-specific microtubule structures is poorly understood ..read more
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Sequence basis of transcription initiation in the human genome | Science
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50m ago
Transcription initiation is a process that is essential to ensuring the proper function of any gene, yet we still lack a unified understanding of sequence patterns and rules that explain most transcription start sites in the human genome. By predicting ..read more
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Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells | Science
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50m ago
Chemical modulation of proteins enables a mechanistic understanding of biology and represents the foundation of most therapeutics. However, despite decades of research, 80% of the human proteome lacks functional ligands. Chemical proteomics has advanced ..read more
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News at a glance: Plants’ tree of life, conserving U.S. federal lands, and entertaining invertebrate sentience
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50m ago
The latest in science and policy ..read more
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A gene mutation turned these fish into intrepid explorers
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50m ago
That behavioral change could explain the remarkable diversity of cichlid fish in Africa’s Lake Tanganyika ..read more
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Can science find ways to ease loneliness?
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50m ago
The health risks of social isolation and loneliness are inspiring government action and a hunt for effective interventions ..read more
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Dangers of disposable electronic devices | Science
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50m ago
HomeScienceVol. 384, No. 6694Dangers of disposable electronic devicesBack To Vol. 384, No. 6694 Full accessLetter Share on Dangers of disposable electronic devicesLaura Young [email protected], Sue Dawson, [...] , David Lavallee, Mark Midownik, [...] , Imogen Napper, Richard Thompson, and Rebecca Wade+4 authors +2 authors fewerAuthors Info & AffiliationsScience25 Apr 2024Vol 384, Issue 6694p. 393 ..read more
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Livestock intensification: No panacea for emissions | Science
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51m ago
During the 28th annual meeting of the Conference of Parties to the UN Framework Convention on Climate Change (COP28) held in November and December 2023, the UN Food and Agriculture Organization (FAO) released a roadmap for transforming food systems. The plan aims to end world hunger without breaching the relatively safe 1.5°C global temperature rise threshold (1). The livestock industry is food systems’ biggest climate culprit, accounting for more than half of food systems emissions (2) and at least 16.5% of all anthropogenic greenhouse gas (GHG) emissions (2, 3). FAO’s roadmap calls for inten ..read more
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Science needs neurodiversity | Science
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51m ago
All brains work differently. Individuals process information and engage with the world in ways that are influenced by a multitude of biological, cultural, and social factors. In the world of science, these differences are what spark innovation. This is ..read more
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