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Cell Discovery

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Cell Discovery is an open access international journal that publishes results of high significance and broad interest in all areas of molecular and cell biology. Cell Discovery is established in 2015 as a sister journal of the high-profile international journal Cell Research. Cell Discovery, published by Springer Nature in partnership with the Center for Excellence in Molecular Cell Science,..

Inter- and trans-generational impacts of real-world PM2.5 exposure on male-specific primary hypogonadism

Cell Discovery

by Xiaoyu Wei, Zhonghao Zhang, Yayun Gu, Rong Zhang, Jie Huang, Feng Li, Yuanlin He, Shuai Lu, Yifei Wu, Wentao Zeng, Xiaorui Liu, Chenzi Liu, Jinyi Liu, Lin Ao, Fuquan Shi, Qing Chen, Yuan Lin, Jiangbo Du, Guangfu Jin, Yankai Xia, Hongxia Ma, Yuxin Zheng, Ran Huo, Jia Cao, Hongbing Shen, Zhibin Hu

11h ago

Cell Discovery, Published online: 23 April 2024; doi:10.1038/s41421-024-00657-0 Inter- and trans-generational impacts of real-world PM2.5 exposure on male-specific primary hypogonadism ..read more

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ANKFY1 bridges ATG2A-mediated lipid transfer from endosomes to phagophores

Cell Discovery

by Bin Wei, Yuhui Fu, Xiuzhi Li, Fang Chen, Yiqing Zhang, Hanmo Chen, Mindan Tong, Linsen Li, Yi Pan, Shen Zhang, She Chen, Xiaoxia Liu, Qing Zhong

1w ago

Cell Discovery, Published online: 16 April 2024; doi:10.1038/s41421-024-00659-y ANKFY1 bridges ATG2A-mediated lipid transfer from endosomes to phagophores ..read more

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Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting

Cell Discovery

by Christoph Gruber, Lea Krautner, Valter Bergant, Vincent Grass, Zhe Ma, Lara Rheinemann, Ariane Krus, Friederike Reinhardt, Lyupka Mazneykova, Marianne Rocha-Hasler, Dong-Jiunn Jeffery Truong, Gil Gregor Westmeyer, Andreas Pichlmair, Gregor Ebert, Florian Giesert, Wolfgang Wurst

1w ago

Cell Discovery, Published online: 12 April 2024; doi:10.1038/s41421-024-00672-1 Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting ..read more

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Integration of 3D bioprinting and multi-algorithm machine learning identified glioma susceptibilities and microenvironment characteristics

Cell Discovery

by Min Tang, Shan Jiang, Xiaoming Huang, Chunxia Ji, Yexin Gu, Ying Qi, Yi Xiang, Emmie Yao, Nancy Zhang, Emma Berman, Di Yu, Yunjia Qu, Longwei Liu, David Berry, Yu Yao

2w ago

Cell Discovery, Published online: 09 April 2024; doi:10.1038/s41421-024-00650-7 Integration of 3D bioprinting and multi-algorithm machine learning identified glioma susceptibilities and microenvironment characteristics ..read more

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Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04

Cell Discovery

by Lijing Zhang, Xuping Xie, Hannan Luo, Runtong Qian, Yang Yang, Hongtao Yu, Jing Huang, Pei-Yong Shi, Qi Hu

2w ago

Cell Discovery, Published online: 09 April 2024; doi:10.1038/s41421-024-00673-0 Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04 ..read more

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Biogenesis of Rab14-positive endosome buds at Golgi–endosome contacts by the RhoBTB3–SHIP164–Vps26B complex

Cell Discovery

by Jingru Wang, Juan Xiong, Shuhan Zhang, Dongchen Li, Qingzhu Chu, Weiping Chang, Lin Deng, Wei-Ke Ji

3w ago

Cell Discovery, Published online: 02 April 2024; doi:10.1038/s41421-024-00651-6 Biogenesis of Rab14-positive endosome buds at Golgi–endosome contacts by the RhoBTB3–SHIP164–Vps26B complex ..read more

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Structural basis for promiscuity in ligand recognition by yjdF riboswitch

Cell Discovery

by Daniel Krochmal, Christina Roman, Anna Lewicka, Yaming Shao, Joseph A. Piccirilli

3w ago

Cell Discovery, Published online: 02 April 2024; doi:10.1038/s41421-024-00663-2 Structural basis for promiscuity in ligand recognition by yjdF riboswitch ..read more

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Mycobacterium tuberculosis inhibits METTL14-mediated m6A methylation of Nox2 mRNA and suppresses anti-TB immunity

Cell Discovery

by Mingtong Ma, Yongjia Duan, Cheng Peng, You Wu, Xinning Zhang, Boran Chang, Fei Wang, Hua Yang, Ruijuan Zheng, Hongyu Cheng, Yuanna Cheng, Yifan He, Jingping Huang, Jinming Lei, Hanyu Ma, Liru Li, Jie Wang, Xiaochen Huang, Fen Tang, Jun Liu, Jinsong Li, Ruoyan Ying, Peng Wang, Wei Sha, Yawei Gao, Lin Wang, Baoxue Ge

3w ago

Cell Discovery, Published online: 29 March 2024; doi:10.1038/s41421-024-00653-4 Mycobacterium tuberculosis inhibits METTL14-mediated m6A methylation of Nox2 mRNA and suppresses anti-TB immunity ..read more

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Microplastics dampen the self-renewal of hematopoietic stem cells by disrupting the gut microbiota-hypoxanthine-Wnt axis

Cell Discovery

by Lingli Jiang, Yishan Ye, Yingli Han, Qiwei Wang, Huan Lu, Jinxin Li, Wenchang Qian, Xin Zeng, Zhaoru Zhang, Yanmin Zhao, Jimin Shi, Yi Luo, Yunfei Qiu, Jun Sun, Jinghao Sheng, He Huang, Pengxu Qian

3w ago

Cell Discovery, Published online: 29 March 2024; doi:10.1038/s41421-024-00665-0 Microplastics dampen the self-renewal of hematopoietic stem cells by disrupting the gut microbiota-hypoxanthine-Wnt axis ..read more

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Fast and flexible profiling of chromatin accessibility and total RNA expression in single nuclei using Microwell-seq3

Cell Discovery

by Fang Ye, Shuang Zhang, Yuting Fu, Lei Yang, Guodong Zhang, Yijun Wu, Jun Pan, Haide Chen, Xinru Wang, Lifeng Ma, Haofu Niu, Mengmeng Jiang, Tingyue Zhang, Danmei Jia, Jingjing Wang, Yongcheng Wang, Xiaoping Han, Guoji Guo

1M ago

Cell Discovery, Published online: 26 March 2024; doi:10.1038/s41421-023-00642-z Fast and flexible profiling of chromatin accessibility and total RNA expression in single nuclei using Microwell-seq3 ..read more

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