Macrophages clean out the tubules
Nature » Nephrology
by Monica Wang
3w ago
Nature Reviews Nephrology, Published online: 01 February 2024; doi:10.1038/s41581-024-00816-2 Macrophages clean out the tubules ..read more
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Design of a renal-sparing antifungal
Nature » Nephrology
by Susan J. Allison
3w ago
Nature Reviews Nephrology, Published online: 30 January 2024; doi:10.1038/s41581-024-00813-5 Design of a renal-sparing antifungal ..read more
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Effects of SGLT2 inhibitors on the metabolic environment and uraemic toxins
Nature » Nephrology
by Ellen F. Carney
3w ago
Nature Reviews Nephrology, Published online: 30 January 2024; doi:10.1038/s41581-024-00814-4 Effects of SGLT2 inhibitors on the metabolic environment and uraemic toxins ..read more
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The multifaceted links between hearing loss and chronic kidney disease
Nature » Nephrology
by Dina Greenberg, Norman D. Rosenblum, Marcello Tonelli
3w ago
Nature Reviews Nephrology, Published online: 29 January 2024; doi:10.1038/s41581-024-00808-2 Chronic kidney disease is associated with a graded and independent excess risk of sensorineural hearing loss. This Review describes how disruption of shared signalling pathways that are important for the development of both the ear and the kidney and/or the presence of clinical drivers, such as specific medications or treatments, may underlie these associations ..read more
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A united vision for cardiovascular–kidney–metabolic health
Nature » Nephrology
by Susan E. Quaggin, Benjamin Magod
3w ago
Nature Reviews Nephrology, Published online: 29 January 2024; doi:10.1038/s41581-024-00812-6 Improved understanding of the interrelated nature of cardiovascular, kidney and metabolic (CKM) health, the development of novel risk prediction equations, and the availability of powerful new therapies provide an opportunity to change the course of CKM health. Achieving such change at a population level will require additional advances to deliver equitable interdisciplinary care ..read more
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The changing landscape of HIV-associated kidney disease
Nature » Nephrology
by Nina E. Diana, Saraladevi Naicker
3w ago
Nature Reviews Nephrology, Published online: 25 January 2024; doi:10.1038/s41581-023-00801-1 The availability of antiretroviral therapy has led to a transformation in the spectrum of kidney diseases associated with HIV infection. This Review describes the changing pattern of kidney diseases associated with HIV infection, their risk factors, methods of evaluating kidney function in patients with HIV and current therapeutic approaches ..read more
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Metabolic alterations in hereditary and sporadic renal cell carcinoma
Nature » Nephrology
by Nathan J. Coffey, M. Celeste Simon
3w ago
Nature Reviews Nephrology, Published online: 22 January 2024; doi:10.1038/s41581-023-00800-2 Renal cell carcinoma is a metabolic disease linked to a variety of alterations in genes that regulate cellular metabolism. Here, the authors examine cell-intrinsic metabolic alterations in hereditary and sporadic renal cell carcinoma, and how they can be exploited to develop novel therapeutic interventions ..read more
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Amplifying the voices of patients with kidney disease
Nature » Nephrology
by Miranda Scanlon
3w ago
Nature Reviews Nephrology, Published online: 22 January 2024; doi:10.1038/s41581-024-00810-8 All patients with kidney disease have the right to have a say in their own clinical care, the provision of health services and research into kidney disease. Patient empowerment and advocacy, especially for those whose views are seldom heard, can be enhanced by working together in communities ..read more
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Health policy for universal, sustainable and equitable kidney care
Nature » Nephrology
by Ricardo Silvariño, Laura Solá
1M ago
Nature Reviews Nephrology, Published online: 18 January 2024; doi:10.1038/s41581-024-00811-7 Treatment of chronic kidney disease requires a comprehensive approach including universal access to early diagnosis and to medications that can slow disease progression. Such equitable access is not only an ethical requirement but can also reduce the financial and human costs of advancing kidney and cardiovascular disease ..read more
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Overcoming barriers to deliver high quality kidney care
Nature » Nephrology
by Adeera Levin
1M ago
Nature Reviews Nephrology, Published online: 11 January 2024; doi:10.1038/s41581-024-00807-3 Overcoming barriers to deliver high-quality care requires an assessment of the contribution of each barrier within a local context. Tools to identify early disease, knowledge of best therapies, access to care providers and medications, and an accountable and integrated health-care system are essential elements of quality care. Education of patients, providers and policy makers in conjunction with advocacy efforts and national policy frameworks are required to deliver high-quality care worldwide ..read more
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