A new era in the science and care of kidney diseases
Nature » Nephrology
by Carmine Zoccali, Francesca Mallamaci, Liz Lightstone, Vivek Jha, Carol Pollock, Katherine Tuttle, Peter Kotanko, Andrzej Wiecek, Hans Joachim Anders, Giuseppe Remuzzi, Kamyar Kalantar-Zadeh, Adeera Levin, Raymond Vanholder
1w ago
Nature Reviews Nephrology, Published online: 04 April 2024; doi:10.1038/s41581-024-00828-y Despite notable progress in basic, clinical and translational nephrology research in the past 50 years, many challenges remain. In this Review, the authors provide an overview of the current status and future directions in nephrology research and patient care ..read more
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Chronic kidney disease and the global public health agenda: an international consensus
Nature » Nephrology
by Anna Francis, Meera N. Harhay, Albert C. M. Ong, Sri Lekha Tummalapalli, Alberto Ortiz, Agnes B. Fogo, Danilo Fliser, Prabir Roy-Chaudhury, Monica Fontana, Masaomi Nangaku, Christoph Wanner, Charu Malik, Anne Hradsky, Dwomoa Adu, Sunita Bavanandan, Ana Cusumano, Laura Sola, Ifeoma Ulasi, Vivekanand Jha
1w ago
Nature Reviews Nephrology, Published online: 03 April 2024; doi:10.1038/s41581-024-00820-6 Addressing the burden of non-communicable diseases is a global public health priority. In this joint Consensus Statement, the American Society of Nephrology, the European Renal Association and the International Society of Nephrology highlight the need to recognize kidney disease as a key driver of premature mortality, in addition to other non-communicable diseases already prioritized by the World Health Organization ..read more
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Combination therapy for kidney disease in people with diabetes mellitus
Nature » Nephrology
by Daniël H. van Raalte, Petter Bjornstad, David Z. I. Cherney, Ian H. de Boer, Paola Fioretto, Daniel Gordin, Frederik Persson, Sylvia E. Rosas, Peter Rossing, Jennifer A. Schaub, Katherine Tuttle, Sushrut S. Waikar, Hiddo J. L. Heerspink
1w ago
Nature Reviews Nephrology, Published online: 03 April 2024; doi:10.1038/s41581-024-00827-z Several new drug classes have been demonstrated to improve kidney outcomes in people with diabetes mellitus. Here, the authors examine the evidence for the efficacy and safety of combination treatment to reduce the progression of diabetic kidney disease ..read more
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Kidney disease: a global health priority
Nature » Nephrology
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1w ago
Nature Reviews Nephrology, Published online: 03 April 2024; doi:10.1038/s41581-024-00829-x The prevalence of kidney disease and its associated morbidity and mortality continue to rise. This crisis cannot be tackled unless kidney disease is made a global public health priority ..read more
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The global landscape of kidney registries: immense challenges and unique opportunities
Nature » Nephrology
by Christopher H. Grant, Fergus J. Caskey, M. Razeen Davids, Manisha Sahay, Aminu K. Bello, Dorothea Nitsch, Samira Bell
1w ago
Nature Reviews Nephrology, Published online: 02 April 2024; doi:10.1038/s41581-024-00833-1 Kidney registries are essential to understanding the burden of kidney disease and facilitating the development of sustainable and effective programs for kidney disease prevention and care. Key barriers to implementation of registries at a global scale include funding and data quality. These issues warrant the attention of the global nephrology community ..read more
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Sex differences in kidney metabolism and DKD
Nature » Nephrology
by Ellen F. Carney
2w ago
Nature Reviews Nephrology, Published online: 28 March 2024; doi:10.1038/s41581-024-00832-2 Sex differences in kidney metabolism and DKD ..read more
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Switching off SOX9 for epithelial recovery after AKI
Nature » Nephrology
by Monica Wang
3w ago
Nature Reviews Nephrology, Published online: 26 March 2024; doi:10.1038/s41581-024-00830-4 Switching off SOX9 for epithelial recovery after AKI ..read more
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Clonal haematopoiesis and AKI
Nature » Nephrology
by Susan J. Allison
3w ago
Nature Reviews Nephrology, Published online: 26 March 2024; doi:10.1038/s41581-024-00831-3 Clonal haematopoiesis and AKI ..read more
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Drug stewardship in chronic kidney disease to achieve effective and safe medication use
Nature » Nephrology
by Rasheeda K. Hall, Rümeyza Kazancıoğlu, Teerawat Thanachayanont, Germaine Wong, Dharshana Sabanayagam, Marisa Battistella, Sofia B. Ahmed, Lesley A. Inker, Erin F. Barreto, Edouard L. Fu, Catherine M. Clase, Juan J. Carrero
1M ago
Nature Reviews Nephrology, Published online: 15 March 2024; doi:10.1038/s41581-024-00823-3 Patients with chronic kidney disease often require complex polypharmacy, require dose adjustments or discontinuation with changes in kidney function, and can be susceptible to the adverse effects of medications. This Review discusses the principles of drug stewardship — that is, the effective, safe and sustainable use of medications — for people with chronic kidney disease ..read more
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Clinical practice recommendations for kidney involvement in tuberous sclerosis complex: a consensus statement by the ERKNet Working Group for Autosomal Dominant Structural Kidney Disorders and the ERA Genes & Kidney Working Group
Nature » Nephrology
by Djalila Mekahli, Roman-Ulrich Müller, Matko Marlais, Tanja Wlodkowski, Stefanie Haeberle, Marta López de Argumedo, Carsten Bergmann, Luc Breysem, Carla Fladrowski, Elizabeth P. Henske, Peter Janssens, François Jouret, John Christopher Kingswood, Jean-Baptiste Lattouf, Marc Lilien, Geert Maleux, Micaela Rozenberg, Stefan Siemer, Olivier Devuyst, Franz Schaefer, David J. Kwiatkowski, Olivier Rouvière, John Bissler
1M ago
Nature Reviews Nephrology, Published online: 05 March 2024; doi:10.1038/s41581-024-00818-0 Care for patients with tuberous sclerosis complex (TSC) should be coordinated by a multidisciplinary team. This Consensus Statement, which involved input from nephrologists, urologists, geneticists, radiologists, interventional radiologists and pathologists as well as patient representatives, provides an overview of TSC-associated kidney manifestations and outlines current recommendations for the management of kidney involvement in TSC ..read more
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