Nurse Nacole
1,232 FOLLOWERS
Nacole Riccaboni is a board-certified registered nurse, blogs about advanced nursing education and being a new nurse. She posts daily nursing tips, bedside nursing resources, practices, along with advice on nursing academics, licensing exams, professionalism, and nursing school success.
Nurse Nacole
12h ago
Category: Fundamentals
In calcium channel blocker poisoning, the endocrine system is affected. As calcium influx triggers the release of insulin, patients poisoned with calcium channel blockers are often hyperglycemic ..read more
Nurse Nacole
1d ago
Category: Fundamentals
A unique feature of calcium channel blocker poisoning is endocrine dysfunction. Like many drugs, calcium channel blockers lose specificity in overdose and thus interfere with other calcium channels within the body ..read more
Nurse Nacole
3d ago
Category: Fundamentals
Dihydropyridine calcium channel blocker (such as amlodipine) toxicity often causes reflex sinus tachycardia from peripheral vasodilation. Calcium channel blockade has little effect on ventricular conduction ..read more
Nurse Nacole
4d ago
Category: Fundamentals
Severe calcium antagonism eventually affects multiple organ systems. Hypotension and bradycardia occur early, and other rhythm disturbances which include AV block of all degrees, sinus arrest, AV dissociation, junctional rhythm and asystole ..read more
Nurse Nacole
4d ago
Category: Fundamentals
In calcium channel antagonist overdoses, there are negative effects on heart rate, contractility, conduction and vascular tone, with the exception of dihydropyridine calcium channel blockers, which tend to result in tachycardia even in toxicity ..read more
Nurse Nacole
6d ago
Category: Fundamentals
In cases of calcium channel antagonists overdose, verapamil has the deadliest profile, combining severe myocardial depression and peripheral vasodilation. Both verapamil and diltiazem act on the heart and blood vessels ..read more
Nurse Nacole
1w ago
Category: Fundamentals
Calcium channel antagonists block the slow calcium channels in the myocardium and vascular smooth muscle, leading to coronary and peripheral vasodilation. They also reduce cardiac contractility, depress SA nodal activity and slow AV conduction ..read more
Nurse Nacole
1w ago
Category: Fundamentals
High-dose insulin improves cardiac output significantly in beta-blocker toxicity from an increase in stroke volume more than heart rate. Dosing of high-dose insulin in humans successfully treated ranges from 0.5 to 22 U/kg/hr ..read more
Nurse Nacole
1w ago
Category: Fundamentals
Despite glucagon's longer history for treatment of beta-blocker toxicity, high-dose insulin is a superior therapy. High-dose insulin is not a vasopressor. It is a profound inotrope with vasodilating properties ..read more
Nurse Nacole
1w ago
Category: Fundamentals
Vomiting is a common complication of glucagon, particularly if administered too rapidly, so the airway should be monitored closely to prevent aspiration. With cumulative large doses, glucagon should be diluted in 5% glucose in water ..read more