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Cellular & Molecular Immunology

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Covering both basic immunology research and clinical applications, Cellular & Molecular Immunology (CMI) provides the latest information and advancements in our understanding of the immunological response of the host, both in vitro and in vivo.

Lkb1 orchestrates γδ T-cell metabolic and functional fitness to control IL-17-mediated autoimmune hepatitis

Cellular & Molecular Immunology

by Zhiqiang Xiao, Shanshan Wang, Liang Luo, Wenkai Lv, Peiran Feng, Yadong Sun, Quanli Yang, Jun He, Guangchao Cao, Zhinan Yin, Meixiang Yang

3h ago

Cellular & Molecular Immunology, Published online: 19 April 2024; doi:10.1038/s41423-024-01163-9 Lkb1 orchestrates γδ T-cell metabolic and functional fitness to control IL-17-mediated autoimmune hepatitis ..read more

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Neuropilin-1high monocytes protect against neonatal inflammation

Cellular & Molecular Immunology

by Xiaoqing Zheng, Wen Lei, Yongmei Zhang, Han Jin, Cha Han, Fan Wu, Chonghong Jia, Ruihong Zeng, Zhanghua Chen, Yuxia Zhang, Haitao Wang, Qiang Liu, Zhi Yao, Ying Yu, Jie Zhou

3h ago

Cellular & Molecular Immunology, Published online: 17 April 2024; doi:10.1038/s41423-024-01157-7 Neuropilin-1high monocytes protect against neonatal inflammation ..read more

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Bypassing PELO-mediated ATPase activation of the NLR is a common pathogenic cause of NLR-associated autoinflammatory diseases

Cellular & Molecular Immunology

by Xiurong Wu, Zhang-Hua Yang, Yue Zheng, Jianfeng Wu, Jiahuai Han

3h ago

Cellular & Molecular Immunology, Published online: 17 April 2024; doi:10.1038/s41423-024-01162-w Bypassing PELO-mediated ATPase activation of the NLR is a common pathogenic cause of NLR-associated autoinflammatory diseases ..read more

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Targeting macrophage metabolism to enhance tumor immunotherapy

Cellular & Molecular Immunology

by Jing Liu, Zhibo Ma, Wenlong Jia, Peixiang Lan

3h ago

Cellular & Molecular Immunology, Published online: 17 April 2024; doi:10.1038/s41423-024-01149-7 Targeting macrophage metabolism to enhance tumor immunotherapy ..read more

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Synthetic biology approaches for improving the specificity and efficacy of cancer immunotherapy

Cellular & Molecular Immunology

by Bo Zhu, Hang Yin, Di Zhang, Meiling Zhang, Xiaojuan Chao, Luca Scimeca, Ming-Ru Wu

1w ago

Cellular & Molecular Immunology, Published online: 11 April 2024; doi:10.1038/s41423-024-01153-x Synthetic biology approaches for improving the specificity and efficacy of cancer immunotherapy ..read more

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GSNOR negatively regulates the NLRP3 inflammasome via S-nitrosation of MAPK14

Cellular & Molecular Immunology

by Qianjin Liu, Lijin Jiao, Mao-Sen Ye, Zhiyu Ma, Jinsong Yu, Ling-Yan Su, Wei-Yin Zou, Lu-Xiu Yang, Chang Chen, Yong-Gang Yao

1w ago

Cellular & Molecular Immunology, Published online: 03 April 2024; doi:10.1038/s41423-024-01155-9 GSNOR negatively regulates the NLRP3 inflammasome via S-nitrosation of MAPK14 ..read more

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Cellular metabolism regulates the differentiation and function of T-cell subsets

Cellular & Molecular Immunology

by Sicong Ma, Yanan Ming, Jingxia Wu, Guoliang Cui

2w ago

Cellular & Molecular Immunology, Published online: 02 April 2024; doi:10.1038/s41423-024-01148-8 Cellular metabolism regulates the differentiation and function of T-cell subsets ..read more

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The chemerin-CMKLR1 axis in keratinocytes impairs innate host defense against cutaneous Staphylococcus aureus infection

Cellular & Molecular Immunology

by Yu Chen, Yan Song, Zhe Wang, Yangfan Lai, Wei Yin, Qian Cai, Miaomiao Han, Yiheng Cai, Yushan Xue, Zhengrong Chen, Xi Li, Jing Chen, Min Li, Huabin Li, Rui He

3w ago

Cellular & Molecular Immunology, Published online: 26 March 2024; doi:10.1038/s41423-024-01152-y The chemerin-CMKLR1 axis in keratinocytes impairs innate host defense against cutaneous Staphylococcus aureus infection ..read more

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Novel insights into regulation of butyrophilin molecules: critical components of cancer immunosurveillance by γδ T cells

Cellular & Molecular Immunology

by Dieter Kabelitz

3w ago

Cellular & Molecular Immunology, Published online: 26 March 2024; doi:10.1038/s41423-024-01138-w Novel insights into regulation of butyrophilin molecules: critical components of cancer immunosurveillance by γδ T cells ..read more

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Aerobic glycolysis enables the effector differentiation potential of stem-like CD4+ T cells to combat cancer

Cellular & Molecular Immunology

by Dawei Zou, Xiaolong Zhang, Shuang Li, Xiang Xiao, Nancy M. Gonzalez, Laurie J. Minze, Xian C. Li, Wenhao Chen

3w ago

Cellular & Molecular Immunology, Published online: 21 March 2024; doi:10.1038/s41423-024-01154-w Aerobic glycolysis enables the effector differentiation potential of stem-like CD4+ T cells to combat cancer ..read more

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