Mechanosensitive release of 5-HT from specialized intestinal epithelial cells
Nature Reviews Gastroenterology & Hepatology
by Constanza Alcaino
4d ago
Nature Reviews Gastroenterology & Hepatology, Published online: 23 November 2022; doi:10.1038/s41575-022-00712-9 Mechanosensitive release of 5-HT from specialized intestinal epithelial cells ..read more
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Targeting hyperactive tRNA modification improves anti-PD1 efficacy
Nature Reviews Gastroenterology & Hepatology
by Eleni Kotsiliti
4d ago
Nature Reviews Gastroenterology & Hepatology, Published online: 23 November 2022; doi:10.1038/s41575-022-00715-6 Targeting hyperactive tRNA modification improves anti-PD1 efficacy ..read more
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Evolving therapeutic landscape of advanced hepatocellular carcinoma
Nature Reviews Gastroenterology & Hepatology
by Chen Yang, Hailin Zhang, Linmeng Zhang, Andrew X. Zhu, René Bernards, Wenxin Qin, Cun Wang
6d ago
Nature Reviews Gastroenterology & Hepatology, Published online: 11 November 2022; doi:10.1038/s41575-022-00704-9 This Review discusses the current and emerging therapeutic landscape for treatment of advanced hepatocellular carcinoma, including molecular-targeted monotherapies, immuno-oncology monotherapies, combination therapies and novel therapeutic approaches ..read more
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The microbiota and the gut–liver axis in primary sclerosing cholangitis
Nature Reviews Gastroenterology & Hepatology
by Johannes R. Hov, Tom H. Karlsen
2w ago
Nature Reviews Gastroenterology & Hepatology, Published online: 09 November 2022; doi:10.1038/s41575-022-00690-y Primary sclerosing cholangitis (PSC) is closely associated with inflammatory bowel disease (IBD) and potentially provides unique insights into the gut–liver axis. This Review explores these links and provides an overview of the gut microbiome in PSC, including PSC–IBD, exploring related hypotheses of disease mechanisms ..read more
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Artificial intelligence and automation in endoscopy and surgery
Nature Reviews Gastroenterology & Hepatology
by François Chadebecq, Laurence B. Lovat, Danail Stoyanov
2w ago
Nature Reviews Gastroenterology & Hepatology, Published online: 09 November 2022; doi:10.1038/s41575-022-00701-y Advances in artificial intelligence (AI) are changing endoscopy and gastrointestinal surgery, including computer-assisted detection and diagnosis, computer-aided navigation, robot-assisted intervention and automated reporting. This Perspective introduces the role of AI in computer-assisted interventions in gastroenterology with insights on regulatory aspects and the challenges ahead ..read more
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Current developments in gastric cancer: from molecular profiling to treatment strategy
Nature Reviews Gastroenterology & Hepatology
by Maria Alsina, Virginia Arrazubi, Marc Diez, Josep Tabernero
2w ago
Nature Reviews Gastroenterology & Hepatology, Published online: 07 November 2022; doi:10.1038/s41575-022-00703-w Gastric and gastro-oesophageal cancer is a leading cause of cancer-related death worldwide with a poor prognosis. This Review provides a comprehensive overview of current treatment strategies set on a molecular basis, and discusses future therapeutic avenues ..read more
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Integrated systems approach to identify environmental factors in intestinal inflammation
Nature Reviews Gastroenterology & Hepatology
by Jordan Hindson
2w ago
Nature Reviews Gastroenterology & Hepatology, Published online: 04 November 2022; doi:10.1038/s41575-022-00708-5 Integrated systems approach to identify environmental factors in intestinal inflammation ..read more
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Investigating two versus three doses of mRNA vaccine in patients with cirrhosis
Nature Reviews Gastroenterology & Hepatology
by Jordan Hindson
2w ago
Nature Reviews Gastroenterology & Hepatology, Published online: 04 November 2022; doi:10.1038/s41575-022-00711-w Investigating two versus three doses of mRNA vaccine in patients with cirrhosis ..read more
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Colonoscopy screening and risk of CRC
Nature Reviews Gastroenterology & Hepatology
by Jordan Hindson
2w ago
Nature Reviews Gastroenterology & Hepatology, Published online: 04 November 2022; doi:10.1038/s41575-022-00709-4 Colonoscopy screening and risk of CRC ..read more
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Follow-up of SER-109 for recurrent C. difficile
Nature Reviews Gastroenterology & Hepatology
by Jordan Hindson
2w ago
Nature Reviews Gastroenterology & Hepatology, Published online: 04 November 2022; doi:10.1038/s41575-022-00710-x Follow-up of SER-109 for recurrent C. difficile ..read more
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