Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines
BMC » Cancer
by Jueyao Zou, Qiong Chen, Yong He, Yanhong Pan, Han Zhao, Junfeng Shi, Zhonghong Wei, Suyun Yu, Yang Zhao, Xin Han, Yin Lu and Wenxing Chen
2d ago
Circulating tumor cell (CTC) clusters play a critical role in carcinoma metastasis. However, the rarity of CTC clusters and the limitations of capture techniques have retarded the research progress. In vitro C ..read more
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Deep learning-assisted diagnosis of benign and malignant parotid tumors based on ultrasound: a retrospective study
BMC » Cancer
by Tian Jiang, Chen Chen, Yahan Zhou, Shenzhou Cai, Yuqi Yan, Lin Sui, Min Lai, Mei Song, Xi Zhu, Qianmeng Pan, Hui Wang, Xiayi Chen, Kai Wang, Jing Xiong, Liyu Chen and Dong Xu
2d ago
To develop a deep learning(DL) model utilizing ultrasound images, and evaluate its efficacy in distinguishing between benign and malignant parotid tumors (PTs), as well as its practicality in assisting clinici ..read more
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Expression of STAT3 and hypoxia markers in long-term surviving malignant glioma patients
BMC » Cancer
by Katerina Dvorakova, Veronika Skarkova, Barbora Vitovcova, Jiri Soukup, Hana Vosmikova, Zuzana Pleskacova, Adam Skarka, Michael Christian Bartos, Petr Krupa, Petra Kasparova, Jiri Petera and Emil Rudolf
2d ago
Glioblastoma is a malignant and aggressive type of central nevous system malignancy characterized by many distinct biological features including extensive hypoxia. Hypoxia in glioblatoma associates with comple ..read more
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CircPHGDH downregulation decreases papillary thyroid cancer progression through miR-122-5p/PKM2 axis
BMC » Cancer
by Jiying Shen, Zhirong Ma, Jin Yang, Tianzhen Qu, Yu Xia, Yingjie Xu, Ming Zhou and Weiwei Liu
2d ago
Although papillary thyroid carcinoma (PTC) has a favorable prognosis, it could affect patient life quality and become a serious threat because of invasion and metastasis. Many investigations have suggested tha ..read more
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PROTAC EZH2 degrader-1 overcomes the resistance of podophyllotoxin derivatives in refractory small cell lung cancer with leptomeningeal metastasis
BMC » Cancer
by Min-xing Shi, Xi Ding, Liang Tang, Wei-jun Cao, Bo Su and Jie Zhang
4d ago
Leptomeningeal metastasis (LM) of small cell lung cancer (SCLC) is a highly detrimental occurrence associated with severe neurological disorders, lacking effective treatment currently. Proteolysis-targeting ch ..read more
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M1A regulator-mediated methylation modification patterns correlated with autophagy to predict the prognosis of hepatocellular carcinoma
BMC » Cancer
by Yingmin Wu, Lian Li, Long Wang, Shenjie Zhang, Zhirui zeng, Jieyu Lu, Zhi Wang, Yewei Zhang, Shilong Zhang, Haiyang Li and Tengxiang Chen
4d ago
N1-methyladenosine (m1A), among the most common internal modifications on RNAs, has a crucial role to play in cancer development. The purpose of this study were systematically investigate the modification charact ..read more
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Integrated clinical and genomic models using machine-learning methods to predict the efficacy of paclitaxel-based chemotherapy in patients with advanced gastric cancer
BMC » Cancer
by Yonghwa Choi, Jangwoo Lee, Keewon Shin, Ji Won Lee, Ju Won Kim, Soohyeon Lee, Yoon Ji Choi, Kyong Hwa Park and Jwa Hoon Kim
4d ago
Paclitaxel is commonly used as a second-line therapy for advanced gastric cancer (AGC). The decision to proceed with second-line chemotherapy and select an appropriate regimen is critical for vulnerable patien ..read more
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Comparative characteristics of early-onset vs. late-onset advanced colorectal cancer: a nationwide study in China
BMC » Cancer
by Hongwei Liu, Huifang Xu, Yin Liu, Yuqian Zhao, Xi Zhang, Yanqin Yu, Lingbin Du, Yunyong Liu, Wenjun Wang, Helu Cao, Li Ma, Juanxiu Huang, Ji Cao, Li Li, Yanping Fan, Xiaofen Gu…
4d ago
The incidence of early-onset colorectal cancer (EOCRC, diagnosed in patients under the age of 50 years) has been increasing around the world. Here, we aimed to systematically identify distinctive features of E ..read more
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Creatine supplementation and resistance training to preserve muscle mass and attenuate cancer progression (CREATINE-52): a protocol for a double-blind randomized controlled trial
BMC » Cancer
by Adriana M Coletta, Lea Haverbeck Simon, Kelsey Maslana, Sarah Taylor, Kish Larson, Pamela A Hansen, Vinay Mathew Thomas, Cornelia M Ulrich, Manish Kohli, Jonathan Chipman, Umang Swami, Sumati Gupta, Benjamin L Maughan and Neeraj Agarwal
6d ago
Muscle mass is important for metastatic prostate cancer survival and quality of life (QoL). The backbone of treatment for men with metastatic castration sensitive prostate cancer (mCSPC) is androgen deprivatio ..read more
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Development and validation of a nomogram for predicting sever cancer-related fatigue in patients with cervical cancer
BMC » Cancer
by ZhiHui Gu, ChenXin Yang, Ke Zhang and Hui Wu
6d ago
Cancer-related fatigue (CRF) has been considered the biggest influencing factor for cancer patients after surgery. This study aimed to develop and validate a nomogram for severe cancer-related fatigue (CRF) pa ..read more
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