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Genes and Immunity

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Genes & Immunity emphasizes studies investigating how genetic, genomic and functional variations affect immune cells and the immune system, and associated processes in the regulation of health and disease. It further highlights articles on the transcriptional and posttranslational control of gene products involved in signaling pathways regulating immune cells, and protective and destructive..

Cytokine profiling and transcriptomics in mononuclear cells define immune variants in Meniere Disease

Genes and Immunity

by Marisa Flook, Elena Rojano, Alvaro Gallego-Martinez, Alba Escalera-Balsera, Patricia Perez-Carpena, M. del Carmen Moleon, Rocio Gonzalez-Aguado, Victoria Rivero de Jesus, Emilio Domínguez-Durán, Lidia Frejo, Juan A. G. Ranea, Jose Antonio Lopez-Escamez

2M ago

Genes & Immunity, Published online: 23 February 2024; doi:10.1038/s41435-024-00260-z Cytokine profiling and transcriptomics in mononuclear cells define immune variants in Meniere Disease ..read more

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Epigenetic reprogramming of CAR T cells for in vivo functional persistence against solid tumors

Genes and Immunity

by Michael Saitakis

2M ago

Genes & Immunity, Published online: 22 February 2024; doi:10.1038/s41435-024-00262-x Epigenetic reprogramming of CAR T cells for in vivo functional persistence against solid tumors ..read more

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Correction: Preclinical models of breast cancer: B6BC, a transplantable hormone receptor-positive C57BL/6 mouse cell line

Genes and Immunity

by Maria Perez-Lanzon, Maria Chiara Maiuri, Carlos Lopez-Otin, Guido Kroemer

2M ago

Genes & Immunity, Published online: 20 February 2024; doi:10.1038/s41435-024-00259-6 Correction: Preclinical models of breast cancer: B6BC, a transplantable hormone receptor-positive C57BL/6 mouse cell line ..read more

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CXCR4 overexpression in chronic lymphocytic leukemia associates with poorer prognosis: A prospective, single-center, observational study

Genes and Immunity

by Xinran Xue, Zhihao Wen, Xin Zhang, Ying Yang, Yifei Li, Ruoxi Liao, Qin Zheng, Yang Fu, Yu Liu, Hongyan Liao

2M ago

Genes & Immunity, Published online: 17 February 2024; doi:10.1038/s41435-024-00258-7 CXCR4 overexpression in chronic lymphocytic leukemia associates with poorer prognosis: A prospective, single-center, observational study ..read more

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Navigating the thymic landscape through development: from cellular atlas to tissue cartography

Genes and Immunity

by Dörte Symmank, Felix Clemens Richter, André F. Rendeiro

2M ago

Genes & Immunity, Published online: 10 February 2024; doi:10.1038/s41435-024-00257-8 Navigating the thymic landscape through development: from cellular atlas to tissue cartography ..read more

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An immunogenomic exome landscape of triple positive primary antiphospholipid patients

Genes and Immunity

by A. Guffroy, L. Jacquel, Y. Seeleuthner, N. Paul, V. Poindron, F. Maurier, V. Delannoy, A. C. Voegeli, P. Zhang, B. Nespola, A. Molitor, M. J. Apithy, P. Soulas-Sprauel, T. Martin, R. E. Voll, S. Bahram, V. Gies, J. L. Casanova, A. Cobat, B. Boisson, R. Carapito, A. S. Korganow

3M ago

Genes & Immunity, Published online: 24 January 2024; doi:10.1038/s41435-024-00255-w An immunogenomic exome landscape of triple positive primary antiphospholipid patients ..read more

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BCL2 inhibition stimulates dendritic cell function for improved anticancer immunotherapy

Genes and Immunity

by Peng Liu, Liwei Zhao, Guido Kroemer, Oliver Kepp

3M ago

Genes & Immunity, Published online: 24 January 2024; doi:10.1038/s41435-024-00256-9 BCL2 inhibition stimulates dendritic cell function for improved anticancer immunotherapy ..read more

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Interferon-γ and its response are determinants of antibody-mediated rejection and clinical outcomes in patients after renal transplantation

Genes and Immunity

by Hao Zhang, Di Zhang, Yue Xu, He Zhang, Zijian Zhang, Xiaopeng Hu

3M ago

Genes & Immunity, Published online: 22 January 2024; doi:10.1038/s41435-024-00254-x Interferon-γ and its response are determinants of antibody-mediated rejection and clinical outcomes in patients after renal transplantation ..read more

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Take my breath away—mitochondrial dysfunction drives CD8+ T cell exhaustion

Genes and Immunity

by Felix Clemens Richter, Mariia Saliutina, Ahmed N. Hegazy, Andreas Bergthaler

3M ago

Genes & Immunity, Published online: 22 January 2024; doi:10.1038/s41435-023-00233-8 Take my breath away—mitochondrial dysfunction drives CD8+ T cell exhaustion ..read more

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Interleukin-18 produced by gastric epithelial cells protects against pre-neoplastic lesions in Helicobacter pylori infection in mice

Genes and Immunity

by Xiaohu Zhao, Dongmei Tong, Richard L. Ferrero

3M ago

Genes & Immunity, Published online: 20 January 2024; doi:10.1038/s41435-024-00253-y Interleukin-18 produced by gastric epithelial cells protects against pre-neoplastic lesions in Helicobacter pylori infection in mice ..read more

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